Latest Research

SPATIOTEMPORAL CONTROL OF NORADRENALINE-DEPENDENT SYNAPTIC TRANSMISSION

Activation of 𝛼1-adrenergic receptors by afferent-derived noradrenaline produces a synaptic current at persists for tens of seconds.

 

Does this reflect the lifetime of extracellular noradrenaline?

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IONIC CURRENT CARRIED BY DELTA GLUTAMATE RECEPTOR-CHANNELS EXCITES
DORSAL RAPHE NEURONS

Activation of Gq-coupled 𝛼1-adrenergic receptors drives action potential firing in serotonin neurons.

 

But what channel carries the current?

Read the article in eLife

Or check out the eLife digest - "Channeling the positive"

DIRECT ACTION OF THE ENDOCANNABINOID 2-AG ON A-TYPE K+ CHANNELS

Endocannabinoids are lipid-signaling molecules mobilized by activation of GqPCRs.

Membrane lipids are known to act directly on ion channels, but do endocannabiniods?

Or check out the highlights in:

Neuron

Nature Reviews Neuroscience

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