IONIC CURRENT CARRIED BY DELTA GLUTAMATE RECEPTOR-CHANNELS EXCITES

DORSAL RAPHE NEURONS

Activation of Gq-coupled 𝛼1-adrenergic receptors drives action potential firing in serotonin neurons.

But what channel carries the current?

Read the article in eLife

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Or check out the eLife digest - "Channeling the positive"

DIRECT ACTION OF THE ENDOCANNABINOID 2-AG ON A-TYPE K+ CHANNELS

Endocannabinoids are lipid-signaling molecules mobilized by activation of GqPCRs.

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Membrane lipids are known to act directly on ion channels, but do endocannabiniods?

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Read the article in Neuron

Or check out the highlights in:

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Neuron

Nature Reviews Neuroscience