POTENTIATION OF NEURONAL ACTIVITY BY TONIC GLUD1 CURRENT IN BRAIN SLICES
In cell lines and brain slices, GluD1 and GluD2 receptors are open in the presumed absence of agonists and carry a tonic current.
But what allows them to be open?
SPATIOTEMPORAL CONTROL OF NORADRENALINE-DEPENDENT SYNAPTIC TRANSMISSION
Activation of 𝛼1-adrenergic receptors by afferent-derived noradrenaline produces a synaptic current at persists for tens of seconds.
Does this reflect the lifetime of extracellular noradrenaline?
IONIC CURRENT CARRIED BY DELTA GLUTAMATE RECEPTOR-CHANNELS EXCITES
DORSAL RAPHE NEURONS
Activation of Gq-coupled 𝛼1-adrenergic receptors drives action potential firing in serotonin neurons.
But what channel carries the current?